Boehringer Ingelheim Frontline Plus Tick & Flea Spot On for Medium Dogs (10kg to 20kg)

Frontline Plus Spot-On for Medium Dogs (10kg-20kg) - Month-Long Tick and Flea Protection Your Dog Can Count On

If you have a medium-sized dog in India - a Beagle, an Indian Pariah, a Cocker Spaniel, or a Lab who hasn't quite hit their full adult weight yet - you already know that ticks and fleas are not just a monsoon problem. They're a year-round reality. Indian brown dog ticks in particular are stubborn, persistent, and genuinely dangerous - they can transmit diseases like Ehrlichiosis, Babesiosis, and Rocky Mountain Spotted Fever, all of which can be life-threatening if not caught in time. And fleas? Beyond the misery of constant itching, they're one of the primary carriers of tapeworms.

The good news is that one of the most trusted names in tick and flea prevention globally has been available in India for decades, and it works. Frontline Plus spot-on is the product millions of pet parents and vets worldwide reach for first - and for good reason.

What Is Frontline Plus Spot-On for Medium Dogs?

• Frontline Plus is a vet-approved, prescription-grade topical spot-on treatment for medium-sized dogs weighing between 10kg and 20kg. It comes as a pack of 3 pipettes - one pipette per month, making it a 3-month supply in a single purchase. Each 1.34ml pipette contains Fipronil (9.8% w/v) and (S)-Methoprene (8.8% w/v), a dual-active formula that addresses both the adult parasites currently on your dog and the next generation of fleas trying to establish themselves in your home.
• It is manufactured by Boehringer Ingelheim India Pvt. Ltd., Bhiwandi - the Indian arm of one of the world's largest and most respected animal health companies. Boehringer Ingelheim acquired Merial Animal Health (the original maker of Frontline) and has continued the product's legacy of efficacy and safety that was built over billions of doses administered globally since the 1990s.
• Browse our full tick and flea spot-on collection or explore the complete dog tick and flea treatment range on Supertails.

Uses and Benefits of Frontline Plus for Medium Dogs

Frontline Plus is used for both active infestations and routine monthly prevention. Here's what it protects against:

• It kills adult fleas within 24 hours of application, stops the entire flea life cycle - including eggs and larvae - for up to 6 weeks, provides up to 4 weeks of protection against ticks including brown dog ticks (Rhipicephalus sanguineus), Ixodes spp., Dermacentor spp., and Amblyomma spp., and kills and controls biting lice infestations. It is also effective in the management of Flea Allergy Dermatitis (FAD) - a condition where flea saliva triggers an intense allergic reaction in sensitive dogs.
• The biggest advantage Frontline Plus has over many alternatives is that it doesn't just kill what's currently on your dog. The S-Methoprene component prevents flea eggs and larvae from developing, which means it actively interrupts the reinfestation cycle. Approximately 95% of a flea problem lives in the environment - on your floors, carpets, furniture, and bedding - not on your dog. By stopping eggs from hatching, Frontline Plus addresses that environmental reservoir too, which is why it delivers better long-term protection than products that only tackle adult fleas.
• For a thorough understanding of the risks ticks and fleas pose and why monthly prevention matters, this blog on tick and flea prevention for dogs is worth reading in full.

Side Effects of Frontline Plus

• Frontline Plus is one of the most extensively tested veterinary antiparasitic products in the world, with a safety record built over decades and billions of applications. The vast majority of dogs experience no side effects at all.
• At the application site, you may notice temporary greasiness or slight hair clumping for a day or two as the solution dries and distributes - this is completely normal and not a cause for concern. In rare cases, some dogs may experience brief, mild skin irritation at the spot where the solution was applied, particularly dogs with very sensitive skin. This typically resolves on its own within 24 to 48 hours.
• Systemic side effects are extremely uncommon at correctly applied doses. However, if your dog licks the application site before it dries - or if another pet licks it - they may experience temporary hypersalivation or mild nausea. This is why it's important to apply the product in a spot your dog cannot reach with their tongue (between the shoulder blades) and to prevent other pets in the household from grooming the treated dog for at least 24 hours after application.
• A small number of individual dogs may show transient neurological signs such as trembling or incoordination if the product makes contact with the mouth or is ingested in significant amounts. If this happens, contact your vet immediately. It is also not recommended for use on sick, convalescent, or underweight dogs without veterinary guidance.

How to Use Frontline Plus Spot-On?

Applying Frontline Plus correctly makes a real difference to how well it works. Here's exactly how to do it:

• First, check your dog's weight before each application to confirm the medium (10-20kg) pack is the right size. If your dog's weight has changed and they now fall into a different category, use the appropriate variant instead.
• Carefully remove one pipette from the pack. Hold it upright and snap or twist off the tip (away from your face and your dog's face). Part the fur at the base of your dog's neck, between the shoulder blades - you want to get the solution directly onto the skin, not onto the fur. Apply the entire contents of the pipette in one spot directly onto the skin. The solution will then self-distribute through the skin's oil layer across the body over the next 24-48 hours.
• A few important rules: do not bathe your dog or allow them to swim for at least 48 hours before and after application. Shampoo strips the skin's natural oil layer, which is the vehicle through which the active ingredients spread across the body. If your dog is bathed too soon after application, the product may not distribute properly and effectiveness will be reduced. Once applied, keep children away from the treated area until it has fully dried, and prevent other pets from licking the application site for 24 hours. Wash your hands thoroughly after handling the pipette.
• Reapply one pipette every 4 weeks for continuous protection. Do not apply more frequently than once every 30 days.
• Feeding guide based on the application: There is no feeding schedule associated with this product - it is applied topically and does not require fasting or any adjustment to your dog's meals.

How Does Frontline Plus Work?

Frontline Plus uses a dual-action mechanism that works on two levels simultaneously - and this is what makes it more effective than single-active antiparasitics.

• Fipronil is a broad-spectrum insecticide that kills adult fleas, ticks, and lice on contact. Once applied to your dog's skin, it is stored in the sebaceous (oil-producing) glands of the skin and continuously re-released onto the skin surface and coat for up to 4 weeks. Fleas and ticks don't need to bite your dog to be affected - contact with the treated skin and fur is enough. Fipronil works by disrupting the central nervous system of the parasite, causing hyper-excitation, paralysis, and death.
• (S)-Methoprene is an insect growth regulator. It has no direct effect on adult ticks. Its role is specifically to prevent flea eggs and larvae from developing into the next stage of their life cycle. When fleas on your treated dog lay eggs - and they will, even after treatment - those eggs contain residual S-Methoprene. The eggs cannot complete their development. This breaks the reinfestation cycle and prevents the environmental flea population from rebuilding. Together, these two ingredients attack the flea problem from both ends: killing what's present now and preventing what would come next.

Safety Advice for Frontline Plus

• This product is strictly for use on dogs weighing 10-20kg. Never use the medium dog pipette on a small dog, a cat, or a puppy below the indicated weight - the dose concentration is calibrated for a specific body weight range and using a larger-dose pipette on a smaller animal creates serious risk of toxicity. Frontline Plus has a separate formulation for cats - do not use the dog version on cats under any circumstances.
• Safe for use in dogs above 8 weeks of age. Safe for use in pregnant, lactating, and breeding dogs at the standard dose. Store at room temperature away from direct sunlight, heat, and moisture. Keep out of reach of children. This product is for veterinary use only and is not for human consumption. Do not apply to broken, irritated, or infected skin. If you are applying Frontline Plus to a dog who is already on other medications, inform your vet beforehand.
• If you are unsure which variant is right for your dog or if you'd like professional guidance before starting treatment, consult a vet on Supertails - it takes minutes.

What If You Miss a Monthly Application?

Frontline Plus works as a monthly preventive - the protection it provides begins to wane after 30 days. If you miss a scheduled application date, apply the next pipette as soon as you remember and restart your monthly schedule from that point. Do not apply two pipettes at once to make up for the gap. A week or two of reduced protection won't cause a crisis in most cases, but during peak tick season in India - particularly the months leading into and following the monsoon - a lapsed application can leave your dog vulnerable. Set a calendar reminder on the day you apply each pipette so the next dose never slips.

All Substitutes

Frontline Plus is one of the most trusted options in its category, but depending on your dog's lifestyle, your household's preference between topical and oral formats, and your vet's recommendation, here are comparable alternatives available on Supertails:

Frontline Plus' advantage within this group is its global track record, the dual-action flea life cycle control, and its topical format which suits dogs who resist oral tablets. If your dog swims or is bathed very frequently, consider discussing oral alternatives like NexGard or Bravecto with your vet - oral products are not affected by bathing frequency.

Quick Tips for Maximum Protection with Frontline Plus

• Always apply to the base of the neck between the shoulder blades - not the top of the head or back - and ensure the solution reaches the skin, not just the coat.
• Avoid bathing your dog for 48 hours before and after application: the day before and the day after application day are the two most critical windows.
• If your dog swims in a pool, lake, or river regularly, note that frequent water exposure can shorten the effective protection window - reapply at the 4-week mark even if the coat looks clean.
• Treat all dogs in the household at the same time - if one dog is left untreated, fleas will simply transfer and re-infest the treated dogs.
• For cats in the same household, use the dedicated Frontline Plus for cats variant - never the dog version.
• After applying, monitor your dog for the first 30 minutes to ensure they don't find a way to lick the application site.
• It is normal to see more fleas on your dog's coat in the first 24 hours after application - fleas move to the surface of the coat as they die. This is the product working, not failing.
• Combine Frontline Plus with a good anti-tick shampoo or spray during peak infestation seasons for maximum protection - browse our tick and flea shampoo range for effective options.
• And keep the area where your dog sleeps clean - washing bedding frequently during tick season reduces environmental reinfestation significantly.

Vets Also Recommend

• Explore the full tick and flea treatment collection for dogs on Supertails.
• Browse all spot-on tick and flea treatments across brands and formats.
• Check our dog preventive care collection to build a complete year-round health routine.
• Support your dog's skin health after a tick or flea infestation with our dog skin care range.
• If your dog has been scratching excessively due to fleas, our dog skin and coat supplements can help with recovery.
• Browse all dog pharmacy products on Supertails. Not sure whether a spot-on, oral tablet, or collar is right for your dog? Consult a vet on Supertails for personalised guidance - it's quick and expert-backed.

Read these blogs from our expert team before or after your next application:

• The Ultimate Remedy for Tick and Flea Removal for Dogs

Disclaimer: Supertails' sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Give Your Medium Dog the Monthly Protection They Deserve

Ticks and fleas don't take breaks - and neither should your dog's protection. Frontline Plus spot-on for medium dogs gives you one of the most clinically proven, globally trusted, and vet-recommended antiparasitic treatments available in India, delivered in a simple once-monthly application that takes less than two minutes.

The 3-pipette pack covers three months of protection. Buy it once, set three calendar reminders, and let Boehringer Ingelheim do the rest.

Add Frontline Plus for Medium Dogs to Cart - Shop Now

FAQs

Which dog breeds typically fall into the 10-20kg (medium) weight category for Frontline Plus?

Common medium-sized Indian breeds and mixes in this weight range include Beagles, Cocker Spaniels, Indian Pariah Dogs (INDogs), Miniature Schnauzers, Whippets, and Labrador Retrievers and Golden Retrievers during their puppy growth phase. Always weigh your dog before each application rather than going by breed alone - especially for growing pups whose weight can change significantly month to month.

How quickly does Frontline Plus start working after application?

Fipronil begins killing fleas within 24 hours of application and ticks within 48 hours. Fleas typically rise to the surface of the coat as they die, so seeing more fleas than usual on your dog's coat in the first 24 hours after applying is actually a sign the product is working - not failing. The environmental flea population takes longer to reduce, typically up to 3 months of consistent monthly use to fully interrupt the life cycle.

Is Frontline Plus safe to use every month long-term?

Yes - Frontline Plus is designed for continuous monthly use and is considered safe for long-term administration in healthy adult dogs. The active ingredients are stored in the skin's oil glands and released gradually; they do not accumulate in the body to dangerous levels at the recommended monthly dose. As with any veterinary product, use it exactly as directed and inform your vet if your dog is on any other medications.

Can I bathe my dog after applying Frontline Plus?

Avoid bathing your dog or allowing them to swim for at least 48 hours after application. The active ingredients spread via the skin's natural oil layer, and washing with shampoo in that window strips that oil layer before the product has fully distributed, reducing its effectiveness. After 48 hours, the product is considered water-resistant, though very frequent bathing (more than once a week) can shorten the effective protection window.

I still see ticks on my dog 2 days after applying Frontline Plus. Has it stopped working?

Not necessarily. Ticks need to come into contact with the treated skin and coat and then die. Ticks that have recently jumped onto your dog from the environment will still crawl through the treated coat and die - but this takes 24 to 48 hours from the moment of contact. If you are seeing live ticks more than 48-72 hours after application and across the full 4-week protection period, consult your vet - they may assess for environmental reinfestation factors or discuss whether an alternative product is more suitable for your specific tick species or location.

My dog swims almost every day. Will Frontline Plus still work?

Frontline Plus is water-resistant after 48 hours, but very frequent swimming or daily bathing can gradually reduce its effectiveness by stripping the oil layer that carries the active ingredients. If your dog is in water daily, your vet may recommend an oral tick prevention product like NexGard or Bravecto instead - oral products are unaffected by bathing and swimming frequency since the active ingredient works through the bloodstream rather than the skin.

I have cats at home. Can I use the same Frontline Plus pipette on my cat?

No - the dog formulations of Frontline Plus should never be used on cats. The dog version contains a higher concentration of (S)-Methoprene than the cat formulation, and cats are significantly more sensitive to certain compounds in the dog formula. Frontline Plus has a dedicated cat variant specifically formulated and dosed for cats. Use only the appropriate species-specific product.

My dog licked the application site. What should I do?

A small amount of contact with the mouth may cause brief hypersalivation or mild nausea. If your dog licked a significant amount of the freshly applied product, contact your vet as a precaution. To prevent this from happening, always apply between the shoulder blades - a point your dog cannot reach - and keep other pets away from the treated area for 24 hours, as they may attempt to groom the treated dog.

Do I need a prescription to buy Frontline Plus on Supertails?

Yes - Frontline Plus is a veterinary prescription product on Supertails. A licensed pharmacy partner handles dispensing, and a vet will verify your order after purchase. If you don't have an existing prescription, a Supertails vet can review your dog's details and provide one if appropriate via the online vet consultation service.

Can I use Frontline Plus on a pregnant or nursing dog?

Yes - Frontline Plus is considered safe for use in pregnant, lactating, and breeding dogs at the recommended dose. This is one of its practical advantages over some other antiparasitic products that carry restrictions during pregnancy. That said, as a standard precaution, always inform your vet that your dog is pregnant or nursing before starting or continuing any parasitic prevention treatment, so they can confirm the product is appropriate in the context of the dog's overall health.