Boehringer Ingelheim Frontline Plus Tick & Flea Spot On for Dogs (2kg to 10kg)

Frontline Plus Spot-On for Small Dogs and Puppies (2kg-10kg) - Big Protection for the Smallest Members of Your Family

If you have a small dog or a puppy at home, you already know they require a different kind of care than their larger counterparts. Everything about them demands more attention - what they eat, how they're handled, which medicines are safe to give, and in what amounts. Tick and flea protection is no different. The product that works perfectly for a 25kg Labrador can be outright dangerous if given to a 4kg Pomeranian puppy. And yet, ticks and fleas don't discriminate by size. A tiny Shih Tzu, a curious Pug puppy, or a young Dachshund exploring the garden is just as likely - sometimes more likely - to pick up parasites as any adult large-breed dog.

Frontline Plus for small dogs and puppies gives parents of smaller breeds the same globally trusted, vet-recommended tick and flea protection that millions of dogs worldwide have relied on - precisely calibrated for dogs between 2kg and 10kg, and safe to use from as early as 8 weeks of age.

What Is Frontline Plus Spot-On for Small Dogs and Puppies (2-10kg)?

• Frontline Plus (2-10kg) is a vet-approved prescription topical spot-on treatment for small-breed dogs and puppies weighing between 2kg and 10kg. Each pack contains 3 pipettes - a 3-month supply at the recommended monthly application schedule. Each pipette contains 0.67ml of solution, with Fipronil (9.8% w/v) and (S)-Methoprene (8.8% w/v) as the dual active ingredients.
• This is a size-specific formulation - the 0.67ml small dog pipette delivers the precise dose calibrated for dogs in the 2-10kg range. It is not interchangeable with the medium, large, or XLarge dog variants, which contain higher volumes of solution. Using a larger-variant pipette on a small dog is a serious overdose risk.
• Manufactured by Boehringer Ingelheim India Pvt. Ltd., Bhiwandi - the Indian subsidiary of one of the world's leading animal health companies - Frontline Plus carries decades of clinical trust and a safety record built across billions of applications globally. Browse the full tick and flea spot-on collection or explore all tick and flea treatments for dogs on Supertails.

Uses and Benefits of Frontline Plus for Small Dogs and Puppies

Frontline Plus (2-10kg) is used both as a treatment for active flea and tick infestations and as a monthly preventive. It protects against:

• Adult fleas - killed within 24 hours of application. Ticks - including Indian brown dog ticks (Rhipicephalus sanguineus), Ixodes spp., Dermacentor spp., and Amblyomma spp. - killed within 48 hours. Biting lice - controlled effectively with monthly use. Flea eggs and larvae - prevented from developing for up to 6 weeks after application, breaking the reinfestation cycle. Flea Allergy Dermatitis (FAD) - by eliminating fleas before they can trigger an allergic reaction in sensitive dogs.
• For small breed dogs, flea protection takes on extra urgency. A single flea bite on a tiny dog causes far more relative distress than on a larger dog. Small dogs also groom themselves more obsessively when uncomfortable, increasing the risk of ingesting fleas - which can lead to tapeworm infections. And because small dogs often spend more time on indoor furniture and in close contact with their humans, a flea infestation in a small-dog household spreads faster through the home environment.
• The 6-week environmental protection from egg and larvae development is particularly valuable for small dog households - it tackles the 95% of the flea life cycle that lives off your pet and in your home, not just the 5% living on your dog.
• Read more about why year-round tick and flea prevention matters in this expert blog on tick and flea remedies for dogs.

Side Effects of Frontline Plus for Small Dogs

• Frontline Plus has one of the strongest safety profiles among tick and flea treatments globally. In small dogs and puppies, the 0.67ml dose is calibrated to be effective while remaining well within safe tolerance limits - provided the correct weight-band variant is used.
• Most dogs experience no side effects at all. At the application site, you may notice mild, temporary greasiness or a slight clumping of the fur for a day or two as the solution distributes and dries. This is normal and resolves on its own.
• Transient skin reactions at the site of application - such as mild redness, local hair loss, or slight itching - are rarely reported and typically resolve without treatment within 24 to 48 hours. If your dog is particularly sensitive and you notice these signs, monitor for a day before contacting your vet.
• If the solution is accidentally ingested - for example, if your dog manages to lick the application spot before it dries, or if another pet in the household licks the treated area - brief hypersalivation or mild nausea may occur. In the rare event of a large accidental oral exposure, contact your vet promptly.
• For very young puppies (8 to 12 weeks old), extra care is needed. Apply the full pipette as directed, keep the puppy warm and dry after application, and monitor closely for the first couple of hours. If anything concerns you, call your vet.

How to Apply Frontline Plus on Small Dogs and Puppies?

• Applying it correctly is just as important as applying it at all - done wrong, the product won't work as intended.
• Remove one pipette from the pack. Hold it upright and tap the narrow part gently to ensure the solution stays in the body of the pipette. Snap or twist off the tip firmly, pointing it away from your face and your dog's face.
• Part the fur at the base of your dog's neck, right between the shoulder blades, until you can clearly see the skin. On small dogs and puppies with thick or long coats - Shih Tzus, Pomeranians, Dachshunds, Maltese - take extra care to ensure you're parting down to the skin and not just applying to the fur. Place the tip of the pipette directly onto the exposed skin and squeeze the entire contents out. Apply in one spot - do not spread it across a wide area.
• Once applied, keep the following in mind:

Do not bathe your dog, allow them to swim, or get them wet for at least 48 hours before and after application. Shampoo strips the skin's natural oils, which are the vehicle through which Fipronil distributes across the body. Keep children away from the treated area until fully dry. Keep other pets away from the treated dog for at least 24 hours, as they may lick the application site. Wash your hands thoroughly after handling the pipette. Reapply once every 4 weeks for continuous protection.

For puppies below 3 months who are being treated for the first time, have your vet confirm the timing and weigh the puppy just before applying to ensure they've reached the 2kg minimum.

How Does Frontline Plus Work?

Here's the simple version: Frontline Plus works from the outside in, using your dog's own skin to distribute the active ingredients.

• Fipronil - once applied to the skin - is absorbed into and stored in the sebaceous (oil) glands beneath the skin's surface. It is then continuously re-released onto the skin and coat over a period of 4 weeks. Ticks and fleas that crawl through the treated coat or come into contact with the treated skin absorb fipronil, which disrupts their nervous system, causing paralysis and death. They don't need to bite your dog to die - contact with the treated coat is enough.
• (S)-Methoprene acts as an insect growth regulator. It specifically targets flea eggs and larvae, preventing them from maturing into adult fleas. When a flea on your treated dog lays eggs, those eggs absorb the S-Methoprene and cannot complete their life cycle. This is the component that protects your home environment, not just your dog - by stopping flea eggs from hatching in your carpets, bedding, and sofa, it prevents the environmental population from rebuilding after treatment.
• Together, these two mechanisms - kill adult parasites now and prevent the next generation from ever developing - are what make Frontline Plus a genuinely comprehensive solution rather than a simple knockdown spray.

Safety Advice for Frontline Plus (Small Dogs 2-10kg)

• This formulation is strictly for dogs weighing between 2kg and 10kg. Do not use any other Frontline Plus variant on a dog in this weight range - the medium dog pipette contains double the volume and is not safe for dogs under 10kg. Similarly, never use the dog formulation on cats. Cats are uniquely sensitive to certain components and must only receive the dedicated Frontline Plus cat variant, available separately on Supertails.
• Only use on dogs aged 8 weeks and above, and weighing at least 2kg. Do not use on dogs below 2kg under any circumstances, as the dose has not been established as safe for sub-2kg animals. Safe for use in pregnant, lactating, and breeding female dogs at the standard dose. Do not apply to broken, infected, or inflamed skin. Do not use on sick, debilitated, or immunocompromised dogs without veterinary guidance. Keep the pipette sealed until use and store in the original packaging at room temperature, away from heat and direct sunlight. Keep out of reach of children.
• If your puppy is on any other medication or has any underlying health condition, consult your vet before applying. You can consult a Supertails vet for quick, expert guidance before the first application.

What If You Miss a Monthly Application?

• Frontline Plus provides approximately 4 weeks of active flea and tick protection per application. If you've missed a dose, apply the next pipette as soon as you remember and reset your monthly schedule from that date. Do not apply two pipettes at the same time to compensate - this provides no additional benefit and may exceed the recommended dose.
• During India's monsoon months and the post-monsoon period, brown dog tick activity peaks significantly. A lapsed application during this window leaves small dogs and puppies with minimal protection at the very time they need it most. Setting a recurring reminder on your phone immediately after each application is one of the single most practical things you can do to stay on schedule.

All Substitutes

Frontline Plus (2-10kg) is among the most well-established options for small dog tick and flea prevention in India. Here are comparable alternatives available on Supertails, depending on your preference for format and coverage:

A note on Bravecto and NexGard: both oral isoxazolines are generally approved only for dogs aged 6 months and above, meaning they are not appropriate for young puppies under 6 months. For puppies between 8 weeks and 6 months, Frontline Plus remains one of the most trusted and widely vet-recommended options.

Quick Tips for Applying Frontline Plus on Small Dogs and Puppies

• Always weigh your dog before each application - small breeds can stay in the 2-10kg range for years, but puppies of larger breeds may cross 10kg sooner than you expect.
• Once they go above 10kg, switch to the medium dog variant.
• For long-coated small breeds like Shih Tzus and Maltese, part the fur very carefully to ensure the solution reaches skin level - applying it onto the coat rather than the skin significantly reduces effectiveness.
• Hold the puppy gently but securely during application - if they squirm and the solution ends up on the wrong part of the body, it won't distribute as well.
• After applying, engage your puppy with a toy or treat for 15-20 minutes to keep them distracted and away from trying to groom or scratch the area.
• Don't apply during or immediately after a bath - always allow at least 48 hours after the last bath before applying.
• For households with both small dogs and cats, always apply the cat-specific Frontline Plus to your cats - never the dog version - on the same day.
• Browse our tick and flea shampoo for dogs for a good emergency knockdown option between monthly applications during peak infestation months.

Vets Also Recommend...

• Browse the full tick and flea treatment range for dogs on Supertails.
• Explore all spot-on tick and flea solutions by brand and format.
• Keep your small dog's preventive health on track with our pet preventive care collection.
• If your puppy is due for deworming alongside tick and flea treatment, browse our dog dewormer collection - it's best to deworm and apply tick prevention in the same monthly routine.
• Support skin recovery after a flea infestation with our dog skin care range.
• Explore all dog pharmacy products on Supertails.
• For personalised advice on your puppy's parasite prevention plan, consult a vet on Supertails - particularly useful for first-time puppy parents navigating vaccines, deworming, and tick prevention schedules simultaneously.

Read these expert-written blogs:

• The Ultimate Remedy for Tick and Flea Removal for Dogs
• Puppy Deworming Schedule: A Complete Guide

Disclaimer: Supertails' sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

The Smallest Dogs Deserve the Most Careful Protection

Small dogs and puppies are often the most vulnerable members of a household when it comes to parasites - and also the most at risk from using the wrong product. Frontline Plus (2-10kg) removes that risk. It's the right dose for your small dog's body, tested safe from as early as 8 weeks, and trusted by vets and pet parents across India and the world for decades.

Three pipettes, three months of protection. Set your reminders and let Frontline Plus handle the rest - so you can go back to enjoying every single minute with your little one.

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FAQs

Can I use this Frontline Plus on my 2-month-old puppy?

Yes - Frontline Plus (2-10kg) is approved for use in puppies from 8 weeks of age and weighing at least 2kg. It is one of the very few tick and flea treatments approved early in a puppy's life. Oral alternatives like NexGard and Bravecto are generally not approved until 6 months of age, making Frontline Plus spot-on particularly important for the 2 to 6 month puppy window. Always confirm your puppy has reached 2kg before applying and weigh them just before the first dose.

Which small dog breeds typically fall in the 2-10kg range?

Shih Tzus, Pugs, Pomeranians, Chihuahuas, Maltese, Dachshunds (miniature), Toy Poodles, Miniature Pinschers, and Yorkshire Terriers typically stay within the 2-10kg range throughout adulthood. Puppies of medium and large breeds - Beagles, Labradors, Golden Retrievers - will be in this weight range during early growth and should be moved to the appropriate larger variant as soon as they cross 10kg.

My small dog weighs exactly 10kg. Should I use this variant or the medium dog one?

The small dog variant is calibrated for dogs up to 10kg. If your dog weighs exactly 10kg, either variant is technically within a safe range - the medium pipette contains a slightly higher concentration designed for dogs in the 10-20kg range. In practice, many vets suggest moving to the medium variant once your dog is reliably at or above 10kg, but confirm this with your vet as it depends on your dog's actual measured weight and overall health status.

My puppy was just vaccinated yesterday. Can I apply Frontline Plus today?

There's no direct contraindication between Frontline Plus and vaccination, but most vets recommend spacing out any new product application by a few days after vaccination, to avoid confusing any post-vaccine reactions with product-related reactions. A 2 to 3 day gap after vaccination before applying Frontline Plus is a common practical guideline - confirm with your vet what they prefer.

I have both a small dog and a cat at home. Can I use the same pack for both?

No - the dog variant of Frontline Plus (2-10kg) must never be used on cats. Cats require their own dedicated Frontline Plus formulation with a different S-Methoprene concentration specifically calibrated for feline safety. Using the dog version on a cat can cause serious adverse reactions. Always purchase the Frontline Plus for cats variant for your cat and apply both on the same day for household-wide protection.

My Shih Tzu has a very thick, long coat. How do I make sure the application works?

Long-coated breeds require extra attention during application to ensure the solution actually reaches the skin rather than sitting on the outer coat. Use your fingers to part the fur all the way down to the skin at the base of the neck before applying. You may need a fine-toothed comb to help with parting on very thick coats. Apply the pipette contents directly onto the exposed skin - not onto the coat. If you're unsure, your groomer or vet can demonstrate the technique on your dog's first application.

How do I know if Frontline Plus is working? My dog is still scratching.

After application, it takes 24 hours for fleas and up to 48 hours for ticks to die. In the first 24-48 hours, you may actually see more fleas on your dog's coat surface as they move upward and become more visible while dying. This is normal and a sign the treatment is active. Persistent scratching beyond 48-72 hours may be due to skin irritation from flea bites that occurred before treatment, or from environmental reinfestation (fleas from carpets, bedding, or other pets jumping back onto your dog). If scratching continues well beyond a week, consult your vet.

Is it safe to use Frontline Plus on a pregnant or nursing small dog?

Yes - Frontline Plus is considered safe for use in pregnant and lactating dogs at the standard weight-appropriate dose. This is an important consideration because small breed dogs tend to have their litters in environments shared with puppies, where flea protection for the mother becomes particularly relevant. Always inform your vet that your dog is pregnant or nursing before starting any new treatment, and use only the correct weight-band variant.

How should I store the unused pipettes after opening the pack?

Keep unused pipettes sealed in their original foil packaging until you're ready to use them. Store at room temperature - ideally below 25°C - away from direct sunlight, heat sources, and moisture. Do not refrigerate. Keep the pack out of reach of children and other pets. Properly stored, the pipettes maintain their potency until the expiry date printed on the packaging.

Can I combine Frontline Plus with a deworming tablet in the same week?

Yes - combining monthly Frontline Plus applications with your quarterly deworming routine is not just fine, it's actually excellent preventive care practice. Fleas are a primary carrier of tapeworms, so keeping both flea infestations and intestinal worms under control simultaneously is the most complete approach. There's no known interaction between Frontline Plus (topical) and standard oral dewormers like Milpro, Eazypet, or Drontal Plus.